Laborathory for Cariovascular Theranostics, as part of the SenoTarg consortium committed to advancing research in aging and cardiovascular health, has released two innovative scientific articles that shed light on new aspects of cardiomyocyte. These works represent significant progress in understanding the mechanisms behind heart aging and stress-induced senescence, key areas of focus for the consortium.

1. A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes
   Published in Communications Biology, 2023
   Authors: Altomare, Claudia; Bartolucci, Chiara; Sala, Luca; and others
   This study introduces a dynamic clamping approach to differentiate chamber-specific cardiomyocytes, providing crucial insights for further research on heart aging and disease treatment.
2. Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging
   Published in Theranostics, 2022
   Authors: Lazzarini, Edoardo; Rendon-Angel, Azucena; and others
   This research highlights how stress-induced premature senescence can affect heart function, mimicking features of natural cardiac aging, and provides a new perspective on heart health in aging populations.

These publications are part of the ongoing efforts of the SenoTarg consortium to deepen understanding of cardiomyocyte aging, with potential implications for novel treatments targeting age-related cardiovascular conditions.